/* Digital Evolution Engine — production design system.
 *
 * Reference register: Linear, Stripe, Vercel, Benchling. Built for biotech
 * professionals reviewing this on behalf of synthesis vendors and pharma
 * customers — every component is intentional, no decorative noise.
 *
 * Architecture:
 *   - Layout: sidebar + top bar + content workspace (Linear-style chrome).
 *   - Color: 6-step neutral grayscale + 1 brand + 4 semantic colors.
 *   - Typography: Inter (UI) + JetBrains Mono (sequences). Strict scale.
 *   - Depth: 5 elevation tiers via shadow + 1px borders, not gradients.
 *   - Motion: 120–280ms cubic-bezier easing, purposeful only.
 */

@import url('https://fonts.googleapis.com/css2?family=Inter:wght@400;500;600;700&family=JetBrains+Mono:wght@400;500;600&display=swap');

:root {
    /* Neutral scale — slate, tuned for biotech readability */
    --gray-0:  #FFFFFF;
    --gray-1:  #FAFBFC;
    --gray-2:  #F4F6F9;
    --gray-3:  #ECEFF3;
    --gray-4:  #E0E5EC;
    --gray-5:  #CBD2DC;
    --gray-6:  #94A0B0;
    --gray-7:  #5B6878;
    --gray-8:  #2E3744;
    --gray-9:  #0E141B;

    /* Brand — deep teal, refined for professional context */
    --brand:           #0E7C9A;
    --brand-deep:      #0A5F77;
    --brand-light:     #1FA3C7;
    --brand-50:        #ECF7FB;
    --brand-100:       #D4ECF3;
    --brand-200:       #A7D8E7;
    --brand-ring:      rgba(14, 124, 154, 0.22);

    /* Semantic */
    --success:         #047857;
    --success-light:   #ECFDF5;
    --warning:         #B45309;
    --warning-light:   #FFFBEB;
    --danger:          #B91C1C;
    --danger-light:    #FEF2F2;
    --info:            #1D4ED8;
    --info-light:      #EFF6FF;

    /* Surfaces (semantic aliases) */
    --bg-app:          var(--gray-2);
    --bg-card:         var(--gray-0);
    --bg-sidebar:      var(--gray-1);
    --bg-subtle:       var(--gray-2);
    --bg-raised:       var(--gray-1);
    --bg-hover:        var(--gray-3);

    /* Ink */
    --ink-strong:      var(--gray-9);
    --ink:             var(--gray-8);
    --ink-soft:        var(--gray-7);
    --ink-faint:       var(--gray-6);
    --ink-disabled:    var(--gray-5);

    --line:            var(--gray-3);
    --line-strong:     var(--gray-4);
    --line-bold:       var(--gray-5);

    /* Elevation — purposeful, never decorative */
    --elev-1:  0 1px 2px rgba(14, 20, 27, 0.04);
    --elev-2:  0 1px 3px rgba(14, 20, 27, 0.06), 0 1px 2px rgba(14, 20, 27, 0.04);
    --elev-3:  0 4px 12px rgba(14, 20, 27, 0.08), 0 2px 4px rgba(14, 20, 27, 0.04);
    --elev-4:  0 12px 28px rgba(14, 20, 27, 0.10), 0 4px 10px rgba(14, 20, 27, 0.05);
    --elev-5:  0 24px 48px rgba(14, 20, 27, 0.14), 0 6px 14px rgba(14, 20, 27, 0.06);

    /* Geometry */
    --r-1: 4px;
    --r-2: 6px;
    --r-3: 8px;
    --r-4: 12px;
    --r-5: 16px;

    /* Type */
    --font-ui:   'Inter', -apple-system, BlinkMacSystemFont, 'SF Pro Text', sans-serif;
    --font-mono: 'JetBrains Mono', 'SF Mono', 'Fira Code', ui-monospace, Menlo, monospace;

    /* Motion */
    --ease:        cubic-bezier(0.22, 1, 0.36, 1);
    --ease-snap:   cubic-bezier(0.4, 0, 0.2, 1);
    --t-fast:      120ms;
    --t-base:      180ms;
    --t-slow:      280ms;

    /* Layout */
    --sidebar-w: 232px;
    --topbar-h:  56px;
}

* { box-sizing: border-box; margin: 0; padding: 0; }

html, body {
    background: var(--bg-app);
    color: var(--ink);
    font-family: var(--font-ui);
    font-size: 14px;
    line-height: 1.55;
    -webkit-font-smoothing: antialiased;
    text-rendering: optimizeLegibility;
    font-feature-settings: 'cv02', 'cv03', 'cv04', 'cv11';
}

body { min-height: 100vh; }

a { color: inherit; text-decoration: none; }
button, input, select, textarea { font-family: inherit; font-size: inherit; color: inherit; }
button { cursor: pointer; border: none; background: none; }
kbd {
    font-family: var(--font-mono);
    font-size: 11px;
    padding: 2px 5px;
    background: var(--gray-3);
    border: 1px solid var(--line-strong);
    border-radius: var(--r-1);
    color: var(--ink-soft);
    box-shadow: 0 1px 0 var(--line-strong);
}

::selection { background: var(--brand-100); color: var(--brand-deep); }

::-webkit-scrollbar { width: 10px; height: 10px; }
::-webkit-scrollbar-track { background: transparent; }
::-webkit-scrollbar-thumb {
    background: var(--gray-4);
    border-radius: 5px;
    border: 2px solid transparent;
    background-clip: padding-box;
}
::-webkit-scrollbar-thumb:hover { background: var(--gray-5); background-clip: padding-box; }

/* ====================================================================== APP */

.app {
    display: grid;
    grid-template-columns: var(--sidebar-w) 1fr;
    min-height: 100vh;
}

/* ================================================================== SIDEBAR */

.sidebar {
    position: sticky;
    top: 0;
    height: 100vh;
    background: var(--bg-sidebar);
    border-right: 1px solid var(--line);
    display: flex;
    flex-direction: column;
    padding: 16px 14px 18px;
    gap: 24px;
}

.brand {
    display: flex;
    align-items: center;
    gap: 10px;
    padding: 6px 8px;
    border-radius: var(--r-2);
    transition: background var(--t-fast) var(--ease);
}
.brand:hover { background: var(--bg-hover); }

.brand-mark {
    width: 28px;
    height: 28px;
    display: inline-flex;
    align-items: center;
    justify-content: center;
    color: var(--brand);
    background: var(--brand-50);
    border-radius: var(--r-2);
}
.brand-mark svg { width: 18px; height: 18px; }

.brand-word {
    font-weight: 700;
    font-size: 15px;
    letter-spacing: -0.01em;
    color: var(--ink-strong);
}

.nav {
    display: flex;
    flex-direction: column;
    gap: 2px;
    flex: 1;
    overflow-y: auto;
}

.nav-section {
    font-size: 10px;
    font-weight: 600;
    letter-spacing: 0.08em;
    text-transform: uppercase;
    color: var(--ink-faint);
    padding: 14px 10px 4px;
}

.nav-item {
    display: flex;
    align-items: center;
    gap: 10px;
    padding: 7px 10px;
    border-radius: var(--r-2);
    color: var(--ink-soft);
    font-size: 13px;
    font-weight: 500;
    transition: all var(--t-fast) var(--ease);
    position: relative;
}
.nav-icon { width: 14px; height: 14px; flex-shrink: 0; color: var(--ink-faint); }
.nav-item:hover { background: var(--bg-hover); color: var(--ink); }
.nav-item:hover .nav-icon { color: var(--ink-soft); }
.nav-item.active {
    background: var(--brand-50);
    color: var(--brand-deep);
    font-weight: 600;
}
.nav-item.active .nav-icon { color: var(--brand); }
.nav-tag {
    margin-left: auto;
    font-size: 11px;
    color: var(--ink-faint);
    background: var(--gray-3);
    padding: 1px 6px;
    border-radius: 999px;
    font-variant-numeric: tabular-nums;
    font-weight: 500;
}
.nav-item.active .nav-tag { background: var(--brand-100); color: var(--brand-deep); }

.sidebar-footer {
    display: flex;
    flex-direction: column;
    gap: 8px;
    border-top: 1px solid var(--line);
    padding-top: 14px;
}

.model-card {
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-3);
    padding: 10px 12px;
}
.model-card-head {
    display: flex;
    justify-content: space-between;
    align-items: center;
    margin-bottom: 4px;
}
.model-card-label {
    font-size: 10px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-faint);
    font-weight: 600;
}
.status-dot {
    width: 6px;
    height: 6px;
    border-radius: 50%;
    background: var(--gray-5);
    display: inline-block;
}
.status-dot.status-on {
    background: var(--success);
    box-shadow: 0 0 0 3px rgba(4, 120, 87, 0.18);
}
.model-card-name {
    font-size: 13px;
    font-weight: 600;
    color: var(--ink-strong);
    margin-bottom: 1px;
}
.model-card-meta {
    font-family: var(--font-mono);
    font-size: 10px;
    color: var(--ink-faint);
    letter-spacing: 0.01em;
}

/* ==================================================================== MAIN */

.content {
    min-width: 0;
    display: flex;
    flex-direction: column;
}

.topbar {
    height: var(--topbar-h);
    /* Fully opaque so rows scrolling underneath don't show through. The
     * previous semi-transparent + blur combination caused visual bleeding
     * with the sticky table header positioned just below. */
    background: var(--bg-app);
    border-bottom: 1px solid var(--line);
    padding: 0 32px;
    display: flex;
    align-items: center;
    justify-content: space-between;
    position: sticky;
    top: 0;
    z-index: 10;
}

.breadcrumb {
    display: flex;
    align-items: center;
    gap: 6px;
    font-size: 13px;
}
.crumb { color: var(--ink-faint); }
.crumb-sep { color: var(--ink-disabled); }
.crumb-active { color: var(--ink-strong); font-weight: 500; }

.topbar-actions { display: flex; gap: 8px; align-items: center; }

.cmd-trigger {
    display: flex;
    align-items: center;
    gap: 8px;
    padding: 6px 10px 6px 10px;
    border: 1px solid var(--line-strong);
    background: var(--gray-0);
    border-radius: var(--r-2);
    color: var(--ink-faint);
    font-size: 13px;
    box-shadow: var(--elev-1);
    transition: all var(--t-fast) var(--ease);
}
.cmd-trigger svg { width: 14px; height: 14px; color: var(--ink-faint); }
.cmd-trigger:hover {
    border-color: var(--line-bold);
    color: var(--ink-soft);
    box-shadow: var(--elev-2);
}
.cmd-trigger span { color: var(--ink-soft); }
.cmd-trigger kbd { margin-left: 16px; }

/* =============================================================== WORKSPACE */

.workspace {
    flex: 1;
    padding: 28px 32px 40px;
    display: flex;
    flex-direction: column;
    gap: 20px;
    max-width: 1180px;
    width: 100%;
}

footer {
    padding: 20px 32px 24px;
    text-align: center;
    border-top: 1px solid var(--line);
    margin-top: auto;
}
.footer-note { font-size: 11px; color: var(--ink-faint); letter-spacing: 0.02em; }

/* =================================================================== HERO */

.hero {
    background:
        radial-gradient(80% 120% at 100% 0%, var(--brand-50) 0%, transparent 55%),
        var(--bg-card);
    border: 1px solid var(--line);
    border-radius: var(--r-4);
    padding: 28px 32px;
    display: grid;
    grid-template-columns: 1fr auto;
    gap: 32px;
    align-items: end;
    box-shadow: var(--elev-1);
}

.eyebrow {
    display: inline-block;
    font-size: 11px;
    font-weight: 600;
    letter-spacing: 0.08em;
    text-transform: uppercase;
    color: var(--brand);
    margin-bottom: 12px;
}

.hero h1 {
    font-size: 28px;
    font-weight: 700;
    letter-spacing: -0.02em;
    color: var(--ink-strong);
    margin-bottom: 8px;
    line-height: 1.15;
}

.hero-lede {
    font-size: 14px;
    color: var(--ink-soft);
    max-width: 56ch;
    line-height: 1.6;
}

.hero-pipeline {
    display: flex;
    align-items: center;
    gap: 8px;
    flex-wrap: wrap;
}
.pipe-step {
    display: flex;
    flex-direction: column;
    gap: 2px;
    padding: 8px 12px;
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    background: var(--gray-0);
    min-width: 92px;
}
.pipe-num {
    font-family: var(--font-mono);
    font-size: 10px;
    color: var(--ink-faint);
    font-weight: 600;
    letter-spacing: 0.04em;
}
.pipe-label {
    font-size: 12px;
    color: var(--ink);
    font-weight: 500;
    white-space: nowrap;
}
.pipe-arrow {
    color: var(--ink-disabled);
    font-size: 14px;
}

@media (max-width: 980px) {
    .hero { grid-template-columns: 1fr; }
    .hero-pipeline { gap: 6px; }
    .pipe-step { min-width: 0; padding: 6px 9px; }
    .pipe-label { font-size: 11px; }
}

/* =================================================================== CARDS */

.card {
    background: var(--bg-card);
    border: 1px solid var(--line);
    border-radius: var(--r-4);
    padding: 24px 28px;
    box-shadow: var(--elev-1);
}

.card-header {
    display: flex;
    align-items: flex-start;
    justify-content: space-between;
    gap: 20px;
    margin-bottom: 20px;
    padding-bottom: 16px;
    border-bottom: 1px solid var(--line);
}

.card-header.results-header { padding-bottom: 20px; }

.card-header-left { display: flex; gap: 14px; align-items: flex-start; flex: 1; min-width: 0; }

.card-header h2 {
    font-size: 16px;
    font-weight: 600;
    letter-spacing: -0.005em;
    color: var(--ink-strong);
    margin-bottom: 2px;
}

.card-sub {
    font-size: 12px;
    color: var(--ink-faint);
    line-height: 1.5;
}

.step-num {
    width: 28px;
    height: 28px;
    flex-shrink: 0;
    border-radius: 50%;
    background: var(--gray-2);
    color: var(--ink-soft);
    font-size: 12px;
    font-weight: 600;
    display: inline-flex;
    align-items: center;
    justify-content: center;
    font-variant-numeric: tabular-nums;
    border: 1px solid var(--line);
}
.step-num.done {
    background: var(--success-light);
    color: var(--success);
    border-color: rgba(4, 120, 87, 0.25);
}
.step-num.done svg { width: 14px; height: 14px; }

/* ==================================================================== TABS */

.input-tabs {
    display: flex;
    gap: 2px;
    margin-bottom: 18px;
    padding: 3px;
    background: var(--gray-2);
    border-radius: var(--r-3);
    width: fit-content;
    border: 1px solid var(--line);
}

.tab {
    display: inline-flex;
    align-items: center;
    gap: 6px;
    padding: 6px 12px;
    border-radius: var(--r-2);
    font-size: 12px;
    font-weight: 500;
    color: var(--ink-soft);
    transition: all var(--t-fast) var(--ease);
}
.tab svg { width: 12px; height: 12px; color: currentColor; opacity: 0.8; }
.tab:hover { color: var(--ink); }
.tab.active {
    background: var(--gray-0);
    color: var(--ink-strong);
    box-shadow: var(--elev-1);
    font-weight: 600;
}
.tab-panel { display: none; }
.tab-panel.active { display: block; }

/* ================================================================ DROPZONE */

.dropzone {
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: center;
    gap: 14px;
    padding: 48px 32px;
    border: 1.5px dashed var(--line-strong);
    border-radius: var(--r-3);
    background: var(--gray-1);
    cursor: pointer;
    transition: all var(--t-base) var(--ease);
    text-align: center;
}
.dropzone:hover, .dropzone.drag {
    border-color: var(--brand);
    background: var(--brand-50);
    border-style: solid;
}

.dz-icon {
    width: 48px;
    height: 48px;
    border-radius: var(--r-3);
    background: var(--gray-0);
    border: 1px solid var(--line-strong);
    display: flex;
    align-items: center;
    justify-content: center;
    color: var(--ink-soft);
    box-shadow: var(--elev-1);
    transition: all var(--t-base) var(--ease);
}
.dz-icon svg { width: 22px; height: 22px; }
.dropzone:hover .dz-icon, .dropzone.drag .dz-icon {
    color: var(--brand);
    border-color: var(--brand-200);
}

.dz-copy { display: flex; flex-direction: column; gap: 2px; }
.dz-copy strong { font-size: 14px; font-weight: 600; color: var(--ink-strong); }
.dz-copy span { font-size: 13px; color: var(--ink-soft); }

.dz-formats {
    font-size: 11px;
    color: var(--ink-faint);
    margin-top: 6px;
    display: flex;
    flex-wrap: wrap;
    gap: 4px;
    justify-content: center;
    letter-spacing: 0.02em;
}

/* ================================================================== INPUTS */

textarea, input[type="text"], input[type="number"], select {
    width: 100%;
    padding: 8px 12px;
    background: var(--gray-0);
    border: 1px solid var(--line-strong);
    border-radius: var(--r-2);
    transition: all var(--t-fast) var(--ease);
    font-family: var(--font-mono);
    font-size: 13px;
    line-height: 1.5;
    color: var(--ink-strong);
    box-shadow: var(--elev-1);
}
textarea { resize: vertical; min-height: 160px; }
select {
    font-family: var(--font-ui);
    cursor: pointer;
    appearance: none;
    background-image: url("data:image/svg+xml;utf8,<svg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 12 8' fill='none' stroke='%235B6878' stroke-width='1.5' stroke-linecap='round'><path d='M2 2l4 4 4-4'/></svg>");
    background-repeat: no-repeat;
    background-position: right 12px center;
    background-size: 10px;
    padding-right: 32px;
}
input:focus, textarea:focus, select:focus {
    outline: none;
    border-color: var(--brand);
    box-shadow: 0 0 0 3px var(--brand-ring);
}

/* ============================================================= PASTE SHELL */

.paste-shell {
    display: flex;
    border: 1px solid var(--line-strong);
    border-radius: var(--r-2);
    background: var(--gray-0);
    overflow: hidden;
    transition: all var(--t-fast) var(--ease);
    box-shadow: var(--elev-1);
}
.paste-shell:focus-within {
    border-color: var(--brand);
    box-shadow: 0 0 0 3px var(--brand-ring);
}

.paste-gutter {
    flex-shrink: 0;
    padding: 10px 10px 10px 14px;
    background: var(--gray-2);
    border-right: 1px solid var(--line);
    color: var(--ink-faint);
    font-family: var(--font-mono);
    font-size: 12px;
    line-height: 1.5;
    text-align: right;
    min-width: 46px;
    overflow: hidden;
    user-select: none;
    white-space: pre;
    font-variant-numeric: tabular-nums;
}
.paste-gutter span { display: block; height: calc(1.5em); }
.paste-gutter span.error-line {
    color: var(--danger);
    font-weight: 600;
    background: var(--danger-light);
}

.paste-shell textarea {
    border: none !important;
    border-radius: 0;
    flex: 1;
    background: transparent;
    box-shadow: none !important;
    overflow: auto;
    white-space: pre;
}

.paste-actions {
    display: flex;
    align-items: center;
    justify-content: space-between;
    gap: 12px;
    margin-top: 12px;
}

.paste-stats {
    font-size: 11px;
    color: var(--ink-faint);
    font-variant-numeric: tabular-nums;
    letter-spacing: 0.04em;
    text-transform: uppercase;
    font-weight: 500;
}

/* ============================================================== BUTTONS */

.primary {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    gap: 10px;
    padding: 12px 22px;
    border-radius: var(--r-2);
    background: var(--ink-strong);
    color: var(--gray-0);
    font-weight: 600;
    font-size: 13px;
    letter-spacing: -0.005em;
    transition: all var(--t-base) var(--ease);
    border: 1px solid var(--ink-strong);
    box-shadow: var(--elev-1);
}
.primary:not(:disabled):hover {
    background: var(--gray-9);
    transform: translateY(-1px);
    box-shadow: var(--elev-3);
}
.primary:not(:disabled):active { transform: translateY(0); box-shadow: var(--elev-2); }
.primary:disabled {
    background: var(--gray-3);
    color: var(--ink-disabled);
    border-color: var(--line-strong);
    cursor: not-allowed;
    box-shadow: none;
}

.primary-lg {
    width: 100%;
    padding: 16px 24px;
    font-size: 14px;
    background: linear-gradient(180deg, var(--brand) 0%, var(--brand-deep) 100%);
    border-color: var(--brand-deep);
    box-shadow: 0 1px 2px rgba(10, 95, 119, 0.20), inset 0 1px 0 rgba(255,255,255,0.16);
}
.primary-lg:not(:disabled):hover {
    background: linear-gradient(180deg, var(--brand-deep) 0%, #07485A 100%);
    box-shadow: 0 6px 16px rgba(14, 124, 154, 0.25), inset 0 1px 0 rgba(255,255,255,0.16);
}
.primary-lg:disabled {
    background: var(--gray-3);
}

.primary-icon {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    width: 26px;
    height: 26px;
    border-radius: var(--r-1);
    background: rgba(255,255,255,0.18);
}
.primary-icon svg { width: 12px; height: 12px; }
.primary:disabled .primary-icon { background: var(--gray-4); color: var(--ink-disabled); }

.primary-content { display: flex; flex-direction: column; align-items: flex-start; gap: 1px; }
.primary-label { font-weight: 600; }
.primary-sub { font-size: 11px; opacity: 0.78; font-weight: 400; letter-spacing: 0; }
.primary:disabled .primary-sub { opacity: 1; }

.primary-ghost {
    padding: 8px 16px;
    border-radius: var(--r-2);
    border: 1px solid var(--line-strong);
    background: var(--gray-0);
    color: var(--ink);
    font-size: 13px;
    font-weight: 500;
    transition: all var(--t-fast) var(--ease);
    box-shadow: var(--elev-1);
}
.primary-ghost:hover {
    background: var(--gray-1);
    border-color: var(--line-bold);
}

.ghost {
    display: inline-flex;
    align-items: center;
    gap: 6px;
    padding: 7px 12px;
    border-radius: var(--r-2);
    border: 1px solid var(--line-strong);
    background: var(--gray-0);
    color: var(--ink-soft);
    font-size: 13px;
    font-weight: 500;
    transition: all var(--t-fast) var(--ease);
    box-shadow: var(--elev-1);
}
.ghost svg { width: 14px; height: 14px; color: currentColor; }
.ghost:hover {
    border-color: var(--brand);
    color: var(--brand-deep);
    background: var(--brand-50);
}
.ghost-sm { padding: 5px 10px; font-size: 12px; }

/* ============================================================= PREVIEW */

.preview {
    margin-top: 20px;
    padding: 18px 20px;
    border-radius: var(--r-3);
    background: var(--gray-1);
    border: 1px solid var(--line);
}
.preview-meta {
    display: flex;
    gap: 32px;
    flex-wrap: wrap;
    margin-bottom: 14px;
}
.preview-meta > div { display: flex; flex-direction: column; gap: 3px; }
.meta-label {
    font-size: 10px;
    color: var(--ink-faint);
    text-transform: uppercase;
    letter-spacing: 0.08em;
    font-weight: 600;
}
.meta-val {
    font-size: 14px;
    font-weight: 600;
    color: var(--ink-strong);
    font-variant-numeric: tabular-nums;
}
.pill {
    padding: 2px 9px;
    border-radius: 999px;
    background: var(--brand-50);
    color: var(--brand-deep);
    font-size: 11px;
    font-weight: 600;
    width: fit-content;
    text-transform: capitalize;
    border: 1px solid var(--brand-100);
}
.preview-seq {
    font-family: var(--font-mono);
    font-size: 12px;
    color: var(--ink);
    word-break: break-all;
    padding: 10px 12px;
    background: var(--gray-0);
    border-radius: var(--r-2);
    border: 1px solid var(--line);
    letter-spacing: 0.02em;
    line-height: 1.6;
}

/* ============================================================ IDENTIFY */

.identify-row {
    margin-top: 14px;
    padding-top: 14px;
    border-top: 1px dashed var(--line-strong);
    display: flex;
    align-items: center;
    gap: 12px;
    flex-wrap: wrap;
}

.identify-btn {
    display: inline-flex;
    align-items: center;
    gap: 6px;
    padding: 7px 12px;
    border-radius: var(--r-2);
    border: 1px solid var(--line-strong);
    background: var(--gray-0);
    color: var(--ink);
    font-size: 12px;
    font-weight: 500;
    transition: all var(--t-fast) var(--ease);
    box-shadow: var(--elev-1);
}
.identify-btn svg { width: 13px; height: 13px; color: currentColor; }
.identify-btn:hover {
    border-color: var(--brand);
    color: var(--brand-deep);
    background: var(--brand-50);
}
.identify-btn:disabled { cursor: progress; opacity: 0.8; }

.identify-hint {
    font-size: 11px;
    color: var(--ink-faint);
    line-height: 1.5;
}

.identify-panel {
    margin-top: 14px;
    padding: 14px 16px;
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-3);
    box-shadow: var(--elev-1);
}
.identify-panel[hidden] { display: none; }

.identify-status {
    display: flex;
    align-items: center;
    gap: 10px;
    font-size: 12px;
    color: var(--ink-soft);
}
.identify-spinner {
    width: 14px;
    height: 14px;
    border: 2px solid var(--gray-3);
    border-top-color: var(--brand);
    border-radius: 50%;
    animation: spin 0.75s linear infinite;
    flex-shrink: 0;
}
@keyframes spin { to { transform: rotate(360deg); } }

.identify-headline {
    display: flex;
    align-items: baseline;
    gap: 10px;
    flex-wrap: wrap;
    padding-bottom: 10px;
    margin-bottom: 12px;
    border-bottom: 1px solid var(--line);
}
.identify-headline strong {
    font-size: 14px;
    color: var(--ink-strong);
    font-weight: 600;
}
.identify-headline .organism {
    font-size: 12px;
    color: var(--ink-soft);
    font-style: italic;
}
.identify-headline .id-pct {
    margin-left: auto;
    padding: 2px 9px;
    border-radius: 999px;
    background: var(--success-light);
    color: var(--success);
    font-size: 11px;
    font-weight: 600;
    font-variant-numeric: tabular-nums;
    border: 1px solid rgba(4, 120, 87, 0.22);
}
.identify-headline .id-pct.id-mid    { background: var(--warning-light); color: var(--warning); border-color: #FDE68A; }
.identify-headline .id-pct.id-low    { background: var(--gray-2);        color: var(--ink-soft); border-color: var(--line-strong); }

.identify-hits {
    display: flex;
    flex-direction: column;
    gap: 8px;
}
.identify-hit {
    display: grid;
    grid-template-columns: auto 1fr auto;
    gap: 12px;
    padding: 9px 12px;
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    background: var(--gray-1);
    font-size: 12px;
}
.identify-hit-acc {
    font-family: var(--font-mono);
    color: var(--brand-deep);
    font-weight: 600;
    font-size: 11px;
}
.identify-hit-desc { color: var(--ink); line-height: 1.5; }
.identify-hit-org { color: var(--ink-soft); font-style: italic; }
.identify-hit-stats {
    font-family: var(--font-mono);
    color: var(--ink-faint);
    font-size: 11px;
    text-align: right;
    font-variant-numeric: tabular-nums;
    white-space: nowrap;
}

.identify-actions {
    display: flex;
    gap: 8px;
    margin-top: 12px;
    flex-wrap: wrap;
}

.identify-error {
    color: var(--danger);
    font-size: 12px;
    line-height: 1.5;
}

/* AlphaFold structure viewer (Mol*). Shown below the BLAST hits when the
   top hit has a UniProt accession. Aspect-ratio'd box so the viewer canvas
   has a stable size regardless of structure dimensions. */
.alphafold-wrap {
    margin-top: 14px;
    padding-top: 14px;
    border-top: 1px solid var(--line);
}
.alphafold-head {
    display: flex;
    align-items: center;
    justify-content: space-between;
    margin-bottom: 10px;
    gap: 12px;
}
.alphafold-head h4 {
    font-size: 12px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-soft);
    font-weight: 700;
    margin: 0;
}
.alphafold-meta {
    font-size: 11px;
    color: var(--ink-faint);
    font-family: var(--font-mono);
}
.alphafold-viewer {
    width: 100%;
    height: 360px;
    border-radius: var(--r-3);
    border: 1px solid var(--line);
    background: #0E141B;
    overflow: hidden;
    position: relative;
}
.alphafold-viewer .msp-plugin { background: #0E141B !important; }
.alphafold-loading {
    position: absolute;
    inset: 0;
    display: flex;
    align-items: center;
    justify-content: center;
    color: var(--gray-3);
    font-size: 12px;
    gap: 10px;
    background: #0E141B;
    z-index: 2;
}
.alphafold-loading .identify-spinner {
    border-color: rgba(255,255,255,0.18);
    border-top-color: var(--brand-light);
}
.alphafold-disclaimer {
    margin-top: 8px;
    font-size: 11px;
    color: var(--ink-faint);
    line-height: 1.5;
}
.alphafold-disclaimer a {
    color: var(--brand-deep);
    text-decoration: underline;
    text-underline-offset: 2px;
}

/* ============================================================ CDS PICKER */

.cds-picker {
    margin-top: 20px;
    padding-top: 20px;
    border-top: 1px solid var(--line);
}
.cds-picker h3 {
    font-size: 14px;
    font-weight: 600;
    color: var(--ink-strong);
    margin-bottom: 4px;
}
.muted { color: var(--ink-faint); font-size: 12px; line-height: 1.5; margin-bottom: 12px; }
.cds-list { display: flex; flex-direction: column; gap: 6px; }

.cds-item {
    display: flex;
    align-items: center;
    gap: 14px;
    padding: 11px 16px;
    border-radius: var(--r-2);
    border: 1px solid var(--line);
    cursor: pointer;
    transition: all var(--t-fast) var(--ease);
    background: var(--gray-0);
}
.cds-item:hover { border-color: var(--line-bold); background: var(--gray-1); }
.cds-item.selected {
    border-color: var(--brand);
    background: var(--brand-50);
    box-shadow: 0 0 0 1px var(--brand);
}
.cds-name { flex: 1; font-weight: 500; font-family: var(--font-mono); font-size: 13px; color: var(--ink-strong); }
.cds-length { color: var(--ink-faint); font-size: 12px; font-variant-numeric: tabular-nums; }
.cds-item.marker .cds-name { color: var(--ink-faint); }
.cds-item.marker::after {
    content: 'marker';
    font-size: 10px;
    font-weight: 600;
    color: var(--warning);
    padding: 2px 8px;
    background: var(--warning-light);
    border-radius: 999px;
    border: 1px solid #FDE68A;
    letter-spacing: 0.02em;
}

/* ============================================================ SETTINGS */

.setting-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(220px, 1fr));
    gap: 18px;
}
.setting { display: flex; flex-direction: column; gap: 5px; }
.setting-name {
    font-size: 13px;
    font-weight: 600;
    color: var(--ink-strong);
}
.setting-hint { font-size: 11px; color: var(--ink-faint); margin-bottom: 6px; line-height: 1.5; }

/* ============================================================ PROGRESS */

.progress-shell {
    margin-top: 18px;
    display: flex;
    flex-direction: column;
    gap: 8px;
}
.progress-bar {
    height: 4px;
    background: var(--gray-3);
    border-radius: 999px;
    overflow: hidden;
}
.progress-fill {
    height: 100%;
    width: 0%;
    background: linear-gradient(90deg, var(--brand), var(--brand-light));
    border-radius: 999px;
    transition: width 400ms var(--ease);
    box-shadow: 0 0 12px rgba(14, 124, 154, 0.4);
}
.progress-meta {
    display: flex;
    justify-content: space-between;
    font-size: 11px;
    color: var(--brand-deep);
    font-variant-numeric: tabular-nums;
    font-weight: 600;
    letter-spacing: 0.04em;
    text-transform: uppercase;
}
.progress-message {
    font-size: 12px;
    color: var(--ink-soft);
    font-family: var(--font-mono);
    line-height: 1.5;
}

/* ============================================================ STATS STRIP */

.stats-strip {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(150px, 1fr));
    gap: 1px;
    background: var(--line);
    border: 1px solid var(--line);
    border-radius: var(--r-3);
    overflow: hidden;
    margin-bottom: 18px;
}
.stat-tile {
    background: var(--gray-0);
    padding: 14px 18px;
    display: flex;
    flex-direction: column;
    gap: 4px;
}
.stat-label {
    font-size: 10px;
    text-transform: uppercase;
    letter-spacing: 0.10em;
    color: var(--ink-faint);
    font-weight: 600;
}
.stat-val {
    font-size: 22px;
    font-weight: 700;
    color: var(--ink-strong);
    font-variant-numeric: tabular-nums;
    letter-spacing: -0.02em;
    line-height: 1.1;
}
.stat-sub {
    font-size: 11px;
    color: var(--ink-faint);
    font-variant-numeric: tabular-nums;
}

/* ============================================================ MUTATION MAP */

.mutmap-card {
    background: var(--gray-1);
    border: 1px solid var(--line);
    border-radius: var(--r-3);
    padding: 18px 20px 20px;
    margin-bottom: 18px;
}
.mutmap-head {
    display: flex;
    justify-content: space-between;
    align-items: flex-start;
    margin-bottom: 14px;
    gap: 16px;
}
.mutmap-head h3 {
    font-size: 13px;
    font-weight: 600;
    color: var(--ink-strong);
    margin-bottom: 2px;
}
.mutmap-head .muted { margin: 0; font-size: 11px; }
.mutmap-legend {
    display: flex;
    align-items: center;
    gap: 8px;
    font-size: 11px;
    color: var(--ink-faint);
}
.lg-dot {
    width: 8px;
    height: 8px;
    border-radius: 50%;
    display: inline-block;
}
.lg-mild   { background: var(--brand-200); }
.lg-mid    { background: var(--brand); }
.lg-strong { background: var(--brand-deep); }

.mutmap-canvas {
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    padding: 16px 14px 10px;
    overflow-x: auto;
}
.mutmap-canvas svg { display: block; width: 100%; height: 140px; }

.mutmap-axis line, .mutmap-axis path { stroke: var(--line-strong); stroke-width: 1; }
.mutmap-axis text {
    font-family: var(--font-mono);
    font-size: 10px;
    fill: var(--ink-faint);
}
.mutmap-stem { stroke: var(--line-strong); stroke-width: 1; }
.mutmap-dot {
    transition: r var(--t-fast) var(--ease), fill var(--t-fast) var(--ease);
    cursor: pointer;
}
.mutmap-dot:hover { stroke: var(--ink-strong); stroke-width: 1.5; }
.mutmap-baseline { stroke: var(--line-strong); stroke-width: 1; }

/* ============================================================== RESULTS */

/* ===== Filter toolbar above the variant table ============================ */

.table-toolbar {
    display: flex;
    align-items: center;
    gap: 12px;
    margin-bottom: 12px;
}

.filter-input-wrap {
    flex: 1;
    position: relative;
    display: flex;
    align-items: center;
}
.filter-input-wrap svg {
    position: absolute;
    left: 11px;
    width: 14px;
    height: 14px;
    color: var(--ink-faint);
    pointer-events: none;
}
.filter-input-wrap input {
    padding-left: 34px;
    padding-right: 32px;
    font-family: var(--font-ui);
    font-size: 13px;
}
.filter-clear {
    position: absolute;
    right: 8px;
    width: 20px;
    height: 20px;
    border-radius: 50%;
    background: var(--gray-3);
    color: var(--ink-soft);
    font-size: 14px;
    line-height: 1;
    display: inline-flex;
    align-items: center;
    justify-content: center;
    transition: all var(--t-fast) var(--ease);
}
.filter-clear:hover { background: var(--gray-4); color: var(--ink); }

.table-count {
    font-size: 12px;
    color: var(--ink-faint);
    font-variant-numeric: tabular-nums;
    white-space: nowrap;
    font-weight: 500;
}

/* ===== Run metadata pills + auto methods ================================= */

.run-meta {
    margin-bottom: 18px;
    padding: 14px 18px;
    background: var(--gray-1);
    border: 1px solid var(--line);
    border-radius: var(--r-3);
    display: flex;
    flex-direction: column;
    gap: 12px;
}
.run-meta-pills {
    display: flex;
    flex-wrap: wrap;
    gap: 6px;
}
.run-pill {
    display: inline-flex;
    align-items: center;
    gap: 4px;
    padding: 4px 10px;
    border-radius: 999px;
    background: var(--gray-0);
    border: 1px solid var(--line-strong);
    font-size: 11px;
    color: var(--ink-soft);
    font-variant-numeric: tabular-nums;
}
.run-pill strong { color: var(--ink-strong); font-weight: 600; }

.run-methods {
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    padding: 12px 14px;
    font-size: 12px;
    color: var(--ink);
    line-height: 1.6;
}
.run-methods-head {
    display: flex;
    align-items: center;
    justify-content: space-between;
    margin-bottom: 6px;
}
.run-methods-head h4 {
    font-size: 11px;
    font-weight: 600;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-faint);
}
.run-methods-body { font-family: var(--font-ui); }
.run-methods-body code {
    font-family: var(--font-mono);
    font-size: 11px;
    background: var(--gray-2);
    padding: 1px 4px;
    border-radius: 3px;
}
.run-methods-body cite {
    font-style: italic;
    color: var(--ink-soft);
}

/* ===== BLOSUM62 mutation classification colors ========================== */

.mut-token {
    display: inline-block;
    padding: 1px 6px;
    border-radius: 4px;
    font-family: var(--font-mono);
    font-size: 11px;
    font-weight: 600;
    border: 1px solid;
    cursor: help;
}
.mut-token + .mut-token { margin-left: 4px; }
.mut-cons       { background: #ECFDF5; color: #047857; border-color: #A7F3D0; }    /* BLOSUM62 ≥ 0 */
.mut-mod        { background: #FFFBEB; color: #B45309; border-color: #FDE68A; }    /* -2..-1 */
.mut-drastic    { background: #FEF2F2; color: #B91C1C; border-color: #FECACA; }    /* ≤ -3 */

/* ===== WT/mutant diff in the sequence block ============================= */

.sequence-block .pos-mut {
    background: var(--brand-50);
    color: var(--brand-deep);
    font-weight: 700;
    padding: 0 2px;
    border-radius: 3px;
    cursor: help;
}

.result-table-wrap {
    /* Self-contained scroll region — both axes scroll inside this wrapper
     * rather than at the page level. Sticky header anchors to the wrapper's
     * top, so no row ever hides behind the page-level topbar (and the very
     * first row, V0001, is always reachable without jumping past it). */
    max-height: 72vh;
    overflow: auto;
    border: 1px solid var(--line);
    border-radius: var(--r-3);
    background: var(--gray-0);
}
.result-table { width: 100%; border-collapse: separate; border-spacing: 0; font-size: 13px; }

.result-table th {
    background: var(--gray-0);
    text-align: left;
    padding: 12px 14px;
    font-weight: 600;
    font-size: 11px;
    color: var(--ink-soft);
    border-bottom: 1px solid var(--line);
    white-space: nowrap;
    text-transform: uppercase;
    letter-spacing: 0.06em;
    position: sticky;
    top: 0;
    z-index: 5;
    user-select: none;
}
.result-table th.num { text-align: right; }
.result-table th.sortable { cursor: pointer; }
.result-table th.sortable:hover { color: var(--ink-strong); background: var(--gray-1); }
.result-table th .sort-ind {
    display: inline-block;
    margin-left: 5px;
    color: var(--ink-disabled);
    font-size: 10px;
    transition: color var(--t-fast) var(--ease);
}
.result-table th.sort-active .sort-ind { color: var(--brand); }

.result-table td {
    padding: 11px 14px;
    border-bottom: 1px solid var(--line);
    vertical-align: top;
    font-variant-numeric: tabular-nums;
}
.result-table tr:last-child > td { border-bottom: none; }
.result-table tr:hover td { background: var(--gray-1); }
.result-table tr.expandable td { cursor: pointer; }
.result-table td.num { text-align: right; font-weight: 500; }
.result-table td.mutations {
    font-family: var(--font-mono);
    font-size: 12px;
    color: var(--brand-deep);
    white-space: nowrap;
    font-weight: 500;
}
.result-table td.rank {
    color: var(--ink-faint);
    font-weight: 600;
    font-family: var(--font-mono);
    font-size: 11px;
}

.result-table th.expand-col { width: 36px; }

.expand-toggle {
    border: 1px solid var(--line-strong);
    background: var(--gray-0);
    color: var(--ink-soft);
    font-size: 13px;
    line-height: 1;
    padding: 3px 7px;
    border-radius: var(--r-1);
    transition: all var(--t-fast) var(--ease);
    box-shadow: var(--elev-1);
}
.expand-toggle:hover { border-color: var(--brand); color: var(--brand-deep); }
.expand-toggle.open {
    transform: rotate(90deg);
    border-color: var(--brand);
    color: var(--brand-deep);
    background: var(--brand-50);
}

.detail-row td {
    background: var(--gray-1) !important;
    padding: 0 !important;
    border-bottom: 1px solid var(--line) !important;
}

.detail-panel {
    display: flex;
    flex-direction: column;
    gap: 20px;
    padding: 22px 24px;
    animation: fadeIn 200ms var(--ease);
}

@keyframes fadeIn {
    from { opacity: 0; transform: translateY(-2px); }
    to   { opacity: 1; transform: translateY(0); }
}

.detail-section h4 {
    font-size: 11px;
    font-weight: 600;
    color: var(--ink-faint);
    text-transform: uppercase;
    letter-spacing: 0.08em;
    margin-bottom: 10px;
}

.pcr-summary {
    display: flex;
    flex-wrap: wrap;
    gap: 28px;
    padding: 14px 18px;
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-2);
}
.pcr-summary > div { display: flex; flex-direction: column; gap: 3px; }
.pcr-summary .pcr-label {
    font-size: 10px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-faint);
    font-weight: 600;
}
.pcr-summary .pcr-val {
    font-size: 14px;
    font-weight: 600;
    color: var(--ink-strong);
    font-variant-numeric: tabular-nums;
}

.primer-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: 12px;
}

.primer-card {
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    padding: 14px 16px;
    display: flex;
    flex-direction: column;
    gap: 10px;
    box-shadow: var(--elev-1);
}
.primer-card-head { display: flex; align-items: baseline; justify-content: space-between; gap: 8px; }
.primer-label {
    font-size: 11px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-soft);
    font-weight: 700;
}
.primer-direction { font-family: var(--font-mono); font-size: 10px; color: var(--ink-faint); }
.primer-seq {
    font-family: var(--font-mono);
    font-size: 13px;
    color: var(--ink-strong);
    background: var(--gray-1);
    padding: 10px 12px;
    border-radius: var(--r-1);
    border: 1px solid var(--line);
    word-break: break-all;
    line-height: 1.55;
    letter-spacing: 0.02em;
}
.primer-stats {
    display: flex;
    gap: 18px;
    font-size: 11px;
    color: var(--ink-soft);
    font-variant-numeric: tabular-nums;
}
.primer-stats span strong { color: var(--ink-strong); font-weight: 600; margin-left: 4px; }
.primer-actions { display: flex; gap: 8px; }

.copy-btn {
    flex: 1;
    padding: 7px 12px;
    border-radius: var(--r-1);
    border: 1px solid var(--line-strong);
    background: var(--gray-0);
    font-size: 12px;
    color: var(--ink-soft);
    font-weight: 500;
    transition: all var(--t-fast) var(--ease);
    box-shadow: var(--elev-1);
}
.copy-btn:hover { border-color: var(--brand); color: var(--brand-deep); }
.copy-btn.copied { background: var(--brand-50); border-color: var(--brand); color: var(--brand-deep); }

/* =================================================== CLONING CUSTOMIZER */

.cloning-section { gap: 14px; }
.cloning-hint {
    font-size: 12px;
    color: var(--ink-soft);
    line-height: 1.55;
    margin: 4px 0 8px;
    max-width: 64ch;
}

.cloning-controls { display: flex; flex-wrap: wrap; gap: 12px; }
.cloning-field { display: flex; flex-direction: column; gap: 5px; flex: 1; min-width: 240px; }
.cloning-field-label {
    font-size: 11px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-faint);
    font-weight: 600;
}
.cloning-field select { width: 100%; }

.cloning-preview {
    margin-top: 4px;
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    background: var(--gray-0);
    overflow: hidden;
}
.cloning-preview:empty { display: none; }

.cloning-meta {
    display: flex;
    flex-wrap: wrap;
    gap: 14px;
    align-items: center;
    padding: 10px 14px;
    background: var(--gray-1);
    border-bottom: 1px solid var(--line);
    font-size: 12px;
    color: var(--ink-soft);
    font-variant-numeric: tabular-nums;
}
.cloning-meta strong { color: var(--ink-strong); font-weight: 700; margin-right: 2px; }
.cloning-legend {
    display: inline-flex;
    align-items: center;
    gap: 10px;
    margin-left: auto;
    font-size: 11px;
    color: var(--ink-faint);
}
.legend-swatch {
    display: inline-block;
    width: 10px;
    height: 10px;
    border-radius: 2px;
    margin-right: 3px;
    vertical-align: middle;
}
.legend-flank { background: #FEF3C7; border: 1px solid #FDE68A; }
.legend-cds   { background: var(--brand-50); border: 1px solid var(--brand-100); }

.cloning-preview-block {
    font-family: var(--font-mono);
    font-size: 12px;
    color: var(--ink-strong);
    background: var(--gray-0);
    padding: 14px 16px;
    line-height: 1.65;
    white-space: pre;
    overflow: auto;
    max-height: 240px;
    letter-spacing: 0.04em;
}
.cloning-preview-block .sec-flank,
.cloning-preview-block .sec-vector_5p,
.cloning-preview-block .sec-vector_3p {
    background: #FEF3C7;
    color: #92400E;
    border-radius: 1px;
}
.cloning-preview-block .sec-cds {
    background: var(--brand-50);
    color: var(--brand-deep);
    border-radius: 1px;
}
.cloning-preview-block .sec-n_tag,
.cloning-preview-block .sec-c_tag {
    background: #FCE7F3;       /* pink-50: distinct from amber + brand */
    color: #9D174D;
    border-radius: 1px;
}
.cloning-preview-block .sec-linker_n,
.cloning-preview-block .sec-linker_c {
    background: #E0E7FF;       /* indigo-50: linker / cleavage site */
    color: #3730A3;
    border-radius: 1px;
}

/* ───── Designer — multi-step picker ──────────────────────────────────── */
.cloning-designer {
    display: flex;
    flex-direction: column;
    gap: 14px;
    margin-top: 4px;
}
.designer-controls {
    display: flex;
    flex-direction: column;
    gap: 12px;
    padding: 16px 18px;
    background: var(--gray-1);
    border: 1px solid var(--line);
    border-radius: var(--r-3);
}
.designer-step { display: flex; flex-direction: column; gap: 6px; }
.designer-step-row {
    flex-direction: row;
    flex-wrap: wrap;
    gap: 12px;
}
.designer-step-row > div { flex: 1; min-width: 180px; display: flex; flex-direction: column; gap: 6px; }
.designer-label {
    font-size: 11px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-faint);
    font-weight: 600;
}
.designer-hint {
    font-size: 12px;
    color: var(--ink-soft);
    line-height: 1.55;
    padding-top: 2px;
}
.designer-hint strong { color: var(--ink-strong); font-weight: 600; }

.designer-preview { display: flex; flex-direction: column; gap: 0; }

.legend-vector { background: #FEF3C7; border: 1px solid #FDE68A; }
.legend-tag    { background: #FCE7F3; border: 1px solid #FBCFE8; }
.legend-linker { background: #E0E7FF; border: 1px solid #C7D2FE; }
.legend-cdsBrand { background: var(--brand-50); border: 1px solid var(--brand-100); }

.cloning-legend { gap: 10px; flex-wrap: wrap; }

.designer-warnings {
    padding: 12px 14px;
    background: var(--gray-0);
    border-top: 1px solid var(--line);
    font-size: 12px;
    line-height: 1.6;
}
.designer-warnings h5 {
    font-size: 11px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-faint);
    font-weight: 700;
    margin-bottom: 8px;
}
.designer-warnings ul { list-style: none; padding: 0; display: flex; flex-direction: column; gap: 6px; }
.designer-warnings li {
    padding: 8px 10px;
    border-radius: var(--r-1);
    border-left: 3px solid;
}
.designer-warnings .warn-high   { background: #FEF2F2; border-color: var(--danger);  color: #7F1D1D; }
.designer-warnings .warn-medium { background: #FFFBEB; border-color: #D97706;        color: #78350F; }
.designer-warnings .warn-low    { background: var(--gray-1); border-color: var(--gray-5); color: var(--ink-soft); }
.designer-warnings.warn-pass    { color: var(--success); font-weight: 600; padding: 10px 14px; }

@media (max-width: 959px) {
    .designer-controls { padding: 14px 14px; gap: 10px; }
    .designer-step-row { flex-direction: column; gap: 10px; }
    .designer-step-row > div { min-width: 0; }
}

.cloning-notes, .cloning-sublabel {
    padding: 0 14px 12px;
    font-size: 12px;
    color: var(--ink-soft);
    line-height: 1.6;
}
.cloning-notes strong { color: var(--ink-strong); font-weight: 700; }
.cloning-sublabel { color: var(--ink-faint); }

@media (max-width: 959px) {
    .cloning-meta { padding: 9px 12px; font-size: 11px; gap: 10px; }
    .cloning-legend { width: 100%; margin-left: 0; }
    .cloning-preview-block { font-size: 11px; padding: 12px 12px; }
    .cloning-notes, .cloning-sublabel { padding: 0 12px 12px; font-size: 11px; }
}

/* ====================================== SYNTH ROW (per-row vendor buttons) */

.synth-row {
    display: flex;
    flex-wrap: wrap;
    align-items: center;
    gap: 8px;
    margin-top: 14px;
    padding: 14px 16px;
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-2);
}
.synth-row-label {
    font-size: 11px;
    color: var(--ink-faint);
    font-weight: 600;
    margin-right: 6px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
}
.synth-row .synth-btn {
    flex: 1;
    min-width: 130px;
    max-width: 220px;
    display: inline-flex;
    align-items: center;
    justify-content: center;
    gap: 6px;
    background: linear-gradient(180deg, var(--brand) 0%, var(--brand-deep) 100%);
    border-color: var(--brand-deep);
    color: var(--gray-0);
    font-weight: 600;
    box-shadow: 0 1px 2px rgba(10, 95, 119, 0.22), inset 0 1px 0 rgba(255,255,255,0.18);
}
.synth-row .synth-btn:hover {
    background: linear-gradient(180deg, var(--brand-deep) 0%, #07485A 100%);
    transform: translateY(-1px);
    box-shadow: 0 4px 10px rgba(14, 124, 154, 0.30), inset 0 1px 0 rgba(255,255,255,0.18);
}
.synth-row .synth-btn.copied {
    background: var(--success);
    border-color: var(--success);
    color: var(--gray-0);
}
.synth-arrow { font-weight: 400; opacity: 0.85; display: inline-block; transition: transform var(--t-fast) var(--ease); }
.synth-row .synth-btn:hover .synth-arrow { transform: translate(2px, -2px); opacity: 1; }

.gc-warn {
    display: inline-block;
    padding: 1px 7px;
    border-radius: 999px;
    background: var(--warning-light);
    color: var(--warning);
    font-size: 10px;
    font-weight: 600;
    margin-left: 6px;
    border: 1px solid #FDE68A;
    letter-spacing: 0.02em;
}

.sequence-block {
    font-family: var(--font-mono);
    font-size: 12px;
    color: var(--ink-strong);
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    padding: 14px 16px;
    line-height: 1.65;
    white-space: pre;
    overflow: auto;
    max-height: 280px;
    letter-spacing: 0.04em;
}
.seq-num {
    color: var(--ink-faint);
    font-weight: 500;
    user-select: none;
}

/* ============================================================ DOWNLOAD MENU */

.download-menu { position: relative; display: inline-block; }
.download-trigger .caret {
    margin-left: 4px;
    font-size: 10px;
    color: var(--ink-faint);
    transition: transform var(--t-fast) var(--ease);
    display: inline-block;
}
.download-trigger.open .caret { transform: rotate(180deg); color: var(--brand); }
.download-menu-items {
    position: absolute;
    top: calc(100% + 6px);
    right: 0;
    min-width: 280px;
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-3);
    box-shadow: var(--elev-4);
    padding: 6px;
    z-index: 50;
    animation: menuIn 140ms var(--ease);
}
@keyframes menuIn {
    from { opacity: 0; transform: translateY(-4px); }
    to   { opacity: 1; transform: translateY(0); }
}
.download-item {
    display: flex;
    flex-direction: column;
    gap: 1px;
    padding: 9px 12px;
    border-radius: var(--r-2);
    color: var(--ink-strong);
    cursor: pointer;
    transition: background var(--t-fast) var(--ease);
}
.download-item:hover { background: var(--gray-2); }
.dl-name { font-size: 13px; font-weight: 600; color: var(--ink-strong); }
.dl-desc { font-size: 11px; color: var(--ink-faint); }

/* ============================================================ VIEWS ROUTER */

.view { display: flex; flex-direction: column; gap: 20px; }
.view[hidden] { display: none; }

/* ============================================================ LIBRARY LIST */

.library-list {
    display: flex;
    flex-direction: column;
    gap: 8px;
}

.lib-row {
    display: grid;
    grid-template-columns: 1fr auto auto auto auto;
    gap: 16px;
    align-items: center;
    padding: 14px 16px;
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    transition: all var(--t-fast) var(--ease);
}
.lib-row:hover { border-color: var(--line-bold); background: var(--gray-1); }

.lib-row-id {
    display: flex;
    flex-direction: column;
    gap: 3px;
    min-width: 0;
}
.lib-row-name {
    font-weight: 600;
    color: var(--ink-strong);
    font-size: 13px;
    white-space: nowrap;
    overflow: hidden;
    text-overflow: ellipsis;
}
.lib-row-meta {
    font-size: 11px;
    color: var(--ink-faint);
    font-variant-numeric: tabular-nums;
}
.lib-row-stat {
    text-align: right;
    font-variant-numeric: tabular-nums;
}
.lib-row-stat-num { font-size: 14px; font-weight: 600; color: var(--ink-strong); }
.lib-row-stat-label {
    font-size: 10px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-faint);
    font-weight: 600;
}
.lib-row-actions { display: flex; gap: 6px; }
.lib-row-actions .ghost { padding: 5px 10px; font-size: 12px; }
.lib-row-actions .ghost-danger:hover {
    border-color: var(--danger);
    color: var(--danger);
    background: var(--danger-light);
}

/* ============================================================ HISTORY */

.history-timeline {
    display: flex;
    flex-direction: column;
    gap: 2px;
    padding-left: 8px;
    position: relative;
}
.history-timeline::before {
    content: '';
    position: absolute;
    top: 12px;
    bottom: 12px;
    left: 10px;
    width: 1px;
    background: var(--line);
}
.hist-item {
    display: grid;
    grid-template-columns: 24px 1fr auto;
    gap: 14px;
    align-items: center;
    padding: 10px 14px 10px 8px;
    border-radius: var(--r-2);
    background: var(--gray-0);
    border: 1px solid var(--line);
    margin-left: 12px;
    position: relative;
    transition: all var(--t-fast) var(--ease);
}
.hist-item:hover { border-color: var(--line-bold); }
.hist-item::before {
    content: '';
    position: absolute;
    left: -16px;
    top: 50%;
    transform: translateY(-50%);
    width: 8px;
    height: 8px;
    border-radius: 50%;
    background: var(--brand);
    border: 2px solid var(--gray-0);
    box-shadow: 0 0 0 1px var(--line);
}
.hist-dot {
    width: 28px;
    height: 28px;
    border-radius: var(--r-2);
    background: var(--brand-50);
    color: var(--brand-deep);
    display: inline-flex;
    align-items: center;
    justify-content: center;
}
.hist-dot svg { width: 14px; height: 14px; }
.hist-body { display: flex; flex-direction: column; gap: 2px; min-width: 0; }
.hist-title { font-size: 13px; font-weight: 500; color: var(--ink-strong); }
.hist-meta {
    font-size: 11px;
    color: var(--ink-faint);
    font-variant-numeric: tabular-nums;
}
.hist-time {
    font-size: 11px;
    color: var(--ink-faint);
    font-variant-numeric: tabular-nums;
    white-space: nowrap;
}

/* ============================================================ DOCS */

.docs-card { max-width: 760px; }
.docs-body {
    display: flex;
    flex-direction: column;
    gap: 28px;
}
.docs-body section { display: flex; flex-direction: column; gap: 10px; }
.docs-body h3 {
    font-size: 15px;
    font-weight: 600;
    color: var(--ink-strong);
    letter-spacing: -0.005em;
    border-bottom: 1px solid var(--line);
    padding-bottom: 6px;
    margin-bottom: 4px;
}
.docs-body p { font-size: 13px; line-height: 1.65; color: var(--ink); }
.docs-list {
    padding-left: 22px;
    font-size: 13px;
    line-height: 1.65;
    color: var(--ink);
}
.docs-list li + li { margin-top: 6px; }
.docs-list code, .docs-body code {
    font-family: var(--font-mono);
    font-size: 12px;
    background: var(--gray-2);
    padding: 1px 6px;
    border-radius: var(--r-1);
    color: var(--ink-strong);
}
.docs-callout {
    margin-top: 6px;
    padding: 12px 14px;
    background: var(--brand-50);
    border: 1px solid var(--brand-100);
    border-radius: var(--r-2);
    font-size: 12px;
    color: var(--brand-deep);
    line-height: 1.6;
}
.docs-table {
    border-collapse: collapse;
    font-size: 13px;
    width: 100%;
    max-width: 480px;
}
.docs-table th, .docs-table td {
    text-align: left;
    padding: 7px 12px;
    border-bottom: 1px solid var(--line);
}
.docs-table th {
    background: var(--gray-1);
    font-size: 11px;
    text-transform: uppercase;
    letter-spacing: 0.06em;
    color: var(--ink-soft);
    font-weight: 600;
}
.docs-citation {
    font-size: 12px !important;
    color: var(--ink-soft) !important;
    line-height: 1.6;
    padding-left: 14px;
    border-left: 2px solid var(--line-strong);
}
.docs-citation cite { font-style: italic; color: var(--ink); }

/* ======================================================= EMPTY STATE */

.empty-state {
    display: flex;
    flex-direction: column;
    align-items: center;
    text-align: center;
    padding: 56px 32px 64px;
    background: var(--bg-card);
    border: 1px dashed var(--line-strong);
    border-radius: var(--r-4);
    gap: 18px;
}
.empty-state[hidden] { display: none; }

.empty-art {
    width: 220px;
    max-width: 100%;
    margin-bottom: 8px;
}
.empty-art img,
.empty-art .empty-art-fallback {
    width: 100%;
    height: auto;
    display: block;
}

.empty-title {
    font-size: 17px;
    font-weight: 600;
    color: var(--ink-strong);
    letter-spacing: -0.01em;
}

.empty-sub {
    font-size: 13px;
    color: var(--ink-soft);
    max-width: 52ch;
    line-height: 1.6;
}
.empty-sub strong { color: var(--ink-strong); font-weight: 600; }

/* ============================================================== ERROR */

.error-banner {
    background: var(--danger-light);
    border: 1px solid #FECACA;
    border-left: 3px solid var(--danger);
    color: var(--danger);
    padding: 14px 18px;
    border-radius: var(--r-2);
    margin-top: 16px;
    font-size: 13px;
    line-height: 1.55;
}
.error-banner strong { display: block; margin-bottom: 4px; font-weight: 700; }
.error-banner > div { margin-top: 6px; color: var(--ink-soft); }
.error-banner code {
    font-family: var(--font-mono);
    background: rgba(185, 28, 28, 0.10);
    padding: 1px 6px;
    border-radius: var(--r-1);
    font-size: 12px;
    color: var(--danger);
    font-weight: 500;
}
.error-hint {
    margin-top: 10px !important;
    padding-top: 10px;
    border-top: 1px dashed #FECACA;
    color: var(--ink-soft);
    font-size: 12px;
    line-height: 1.55;
}

/* ============================================================== MODAL (Twist) */

.modal {
    position: fixed;
    inset: 0;
    z-index: 200;
    display: flex;
    align-items: center;
    justify-content: center;
    padding: 24px;
}
.modal[hidden] { display: none; }
.modal-backdrop {
    position: absolute;
    inset: 0;
    background: rgba(14, 20, 27, 0.45);
    backdrop-filter: blur(2px);
    animation: backdropIn 180ms var(--ease);
}
@keyframes backdropIn { from { opacity: 0; } to { opacity: 1; } }

.modal-panel {
    position: relative;
    background: var(--gray-0);
    border: 1px solid var(--line);
    border-radius: var(--r-4);
    box-shadow: var(--elev-5);
    max-width: 640px;
    width: 100%;
    max-height: calc(100vh - 48px);
    display: flex;
    flex-direction: column;
    animation: panelIn 220ms var(--ease);
}
@keyframes panelIn {
    from { opacity: 0; transform: translateY(8px) scale(0.985); }
    to   { opacity: 1; transform: translateY(0) scale(1); }
}

.modal-header {
    display: flex;
    justify-content: space-between;
    align-items: flex-start;
    padding: 18px 22px 14px;
    border-bottom: 1px solid var(--line);
    gap: 16px;
}
.modal-header h2 {
    font-size: 16px;
    font-weight: 600;
    color: var(--ink-strong);
    margin-bottom: 2px;
    letter-spacing: -0.005em;
}
.modal-sub { font-size: 12px; color: var(--ink-faint); }

.modal-close {
    width: 30px;
    height: 30px;
    border-radius: var(--r-2);
    background: transparent;
    color: var(--ink-faint);
    font-size: 22px;
    line-height: 1;
    transition: all var(--t-fast) var(--ease);
    flex-shrink: 0;
}
.modal-close:hover { background: var(--gray-2); color: var(--ink); }

.modal-body {
    padding: 18px 22px 22px;
    overflow-y: auto;
}

.modal-loading {
    display: flex;
    align-items: center;
    gap: 12px;
    padding: 20px 0;
    color: var(--ink-soft);
    font-size: 13px;
}

/* ===== Twist quote display ============================================ */

.quote-hero {
    background: linear-gradient(180deg, var(--brand-50) 0%, var(--gray-0) 100%);
    border: 1px solid var(--brand-100);
    border-radius: var(--r-3);
    padding: 14px 18px 16px;
    margin-bottom: 16px;
}
.quote-hero-row {
    display: flex;
    justify-content: space-between;
    align-items: center;
    gap: 12px;
    margin-bottom: 10px;
}
.quote-hero-numbers {
    display: grid;
    grid-template-columns: 1fr auto 1fr;
    gap: 14px;
    align-items: center;
}
.quote-hero-num { display: flex; flex-direction: column; gap: 2px; }
.quote-hero-label {
    font-size: 10px;
    text-transform: uppercase;
    letter-spacing: 0.08em;
    color: var(--ink-faint);
    font-weight: 600;
}
.quote-hero-val {
    font-size: 30px;
    font-weight: 700;
    color: var(--ink-strong);
    font-variant-numeric: tabular-nums;
    letter-spacing: -0.02em;
    line-height: 1.1;
}
.quote-hero-unit {
    font-size: 16px;
    font-weight: 500;
    color: var(--ink-soft);
    letter-spacing: 0;
    margin-left: 2px;
}
.quote-hero-divider {
    width: 1px;
    height: 36px;
    background: var(--line);
}

.quote-headline {
    display: grid;
    grid-template-columns: 1fr auto;
    gap: 12px;
    padding-bottom: 14px;
    border-bottom: 1px solid var(--line);
    margin-bottom: 16px;
}
.quote-id {
    font-family: var(--font-mono);
    font-size: 11px;
    color: var(--ink-faint);
    text-transform: uppercase;
    letter-spacing: 0.06em;
}
.quote-total {
    font-size: 22px;
    font-weight: 700;
    color: var(--ink-strong);
    font-variant-numeric: tabular-nums;
    letter-spacing: -0.02em;
}
.quote-total-label { font-size: 11px; color: var(--ink-faint); text-transform: uppercase; letter-spacing: 0.06em; }
.quote-status-pill {
    align-self: start;
    padding: 4px 10px;
    border-radius: 999px;
    font-size: 11px;
    font-weight: 600;
    border: 1px solid;
    background: var(--success-light);
    color: var(--success);
    border-color: rgba(4, 120, 87, 0.22);
}
.quote-status-pill.review {
    background: var(--warning-light);
    color: var(--warning);
    border-color: #FDE68A;
}

.quote-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(140px, 1fr));
    gap: 1px;
    background: var(--line);
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    overflow: hidden;
    margin-bottom: 16px;
}
.quote-tile {
    background: var(--gray-0);
    padding: 12px 14px;
    display: flex;
    flex-direction: column;
    gap: 3px;
}
.quote-tile .label {
    font-size: 10px;
    color: var(--ink-faint);
    text-transform: uppercase;
    letter-spacing: 0.08em;
    font-weight: 600;
}
.quote-tile .val {
    font-size: 14px;
    font-weight: 600;
    color: var(--ink-strong);
    font-variant-numeric: tabular-nums;
}

.quote-lineitems {
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    overflow: hidden;
    margin-bottom: 16px;
}
.qli {
    display: grid;
    grid-template-columns: 1fr auto auto;
    gap: 12px;
    padding: 10px 14px;
    border-bottom: 1px solid var(--line);
    align-items: center;
}
.qli:last-child { border-bottom: none; }
.qli-name {
    font-family: var(--font-mono);
    font-size: 12px;
    color: var(--ink-strong);
    font-weight: 600;
}
.qli-meta {
    font-size: 11px;
    color: var(--ink-faint);
    font-variant-numeric: tabular-nums;
}
.qli-price {
    font-weight: 600;
    color: var(--ink-strong);
    font-variant-numeric: tabular-nums;
}

.complexity-row {
    display: flex;
    flex-wrap: wrap;
    gap: 5px;
    margin-top: 6px;
}
.complexity-flag {
    display: inline-block;
    padding: 1px 8px;
    border-radius: 999px;
    font-size: 10px;
    font-weight: 600;
    text-transform: uppercase;
    letter-spacing: 0.04em;
    background: var(--warning-light);
    color: var(--warning);
    border: 1px solid #FDE68A;
}
.complexity-flag.biosec {
    background: var(--danger-light);
    color: var(--danger);
    border-color: #FECACA;
}

.quote-actions {
    display: flex;
    gap: 8px;
    justify-content: flex-end;
}

/* ===== Twist order form =============================================== */

.order-form {
    display: flex;
    flex-direction: column;
    gap: 14px;
}
.order-form-grid {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 12px;
}
.order-form-grid .field-full { grid-column: 1 / -1; }
.order-field { display: flex; flex-direction: column; gap: 4px; }
.order-field label {
    font-size: 11px;
    text-transform: uppercase;
    letter-spacing: 0.06em;
    color: var(--ink-faint);
    font-weight: 600;
}
.order-field input { font-family: var(--font-ui); font-size: 13px; }

.order-terms {
    display: flex;
    gap: 8px;
    align-items: flex-start;
    padding: 10px 12px;
    background: var(--gray-1);
    border: 1px solid var(--line);
    border-radius: var(--r-2);
    font-size: 12px;
    color: var(--ink-soft);
    line-height: 1.5;
}
.order-terms input { width: 16px; height: 16px; margin-top: 2px; box-shadow: none; }

/* ===== Order confirmation =============================================== */

.order-confirm {
    text-align: center;
    padding: 12px 8px;
}
.order-confirm .checkmark {
    width: 56px;
    height: 56px;
    margin: 8px auto 14px;
    border-radius: 50%;
    background: var(--success-light);
    color: var(--success);
    display: flex;
    align-items: center;
    justify-content: center;
    border: 1px solid rgba(4,120,87,0.22);
}
.order-confirm .checkmark svg { width: 28px; height: 28px; }
.order-confirm h3 {
    font-size: 18px;
    font-weight: 600;
    color: var(--ink-strong);
    margin-bottom: 8px;
}
.order-confirm .order-id {
    font-family: var(--font-mono);
    font-size: 14px;
    font-weight: 700;
    color: var(--brand-deep);
    background: var(--brand-50);
    padding: 4px 12px;
    border-radius: var(--r-2);
    display: inline-block;
    margin-bottom: 14px;
}
.order-confirm .order-detail {
    font-size: 13px;
    color: var(--ink-soft);
    line-height: 1.6;
    margin-bottom: 14px;
}

/* ============================================================= TOAST */

.toast {
    position: fixed;
    top: 0;
    left: 50%;
    transform: translate(-50%, -100%);
    z-index: 1000;
    background: var(--ink-strong);
    color: var(--gray-0);
    padding: 12px 22px;
    border-radius: 999px;
    margin-top: 20px;
    font-size: 13px;
    font-weight: 500;
    box-shadow: var(--elev-5);
    display: flex;
    align-items: center;
    gap: 12px;
    max-width: calc(100vw - 64px);
    opacity: 0;
    transition: transform 280ms var(--ease), opacity 200ms var(--ease);
    pointer-events: none;
}
.toast.toast-in  { transform: translate(-50%, 0); opacity: 1; }
.toast.toast-out { transform: translate(-50%, -120%); opacity: 0; }
.toast-check {
    width: 20px;
    height: 20px;
    border-radius: 50%;
    background: var(--brand);
    color: var(--gray-0);
    display: inline-flex;
    align-items: center;
    justify-content: center;
    font-size: 12px;
    font-weight: 700;
    flex-shrink: 0;
}
.toast-msg { line-height: 1.4; }
.toast-warn { background: #78350F; }
.toast-warn .toast-check { background: var(--warning); }

/* =========================================================== RESPONSIVE
 * Mobile-first stack:
 *   < 960 px (phone + small tablet) : sidebar becomes a slide-out drawer
 *                                     triggered from a hamburger button in
 *                                     the topbar; topbar collapses; cards,
 *                                     stats strip, modals, tables all tighten.
 *   ≥ 960 px (desktop)               : full layout above this block.
 */

/* Hamburger button — surfaced only on phone/tablet. */
.nav-toggle {
    display: none;
    align-items: center;
    justify-content: center;
    width: 40px;
    height: 40px;
    border-radius: var(--r-2);
    color: var(--ink-soft);
    border: 1px solid var(--line-strong);
    background: var(--gray-0);
    box-shadow: var(--elev-1);
    margin-right: 10px;
    -webkit-tap-highlight-color: transparent;
    transition: all var(--t-fast) var(--ease);
}
.nav-toggle:hover, .nav-toggle:active {
    border-color: var(--brand);
    color: var(--brand-deep);
    background: var(--brand-50);
}
.nav-toggle svg { width: 18px; height: 18px; }

/* Backdrop that covers the workspace when the drawer is open. */
.sidebar-scrim {
    position: fixed;
    inset: 0;
    background: rgba(14, 20, 27, 0.45);
    z-index: 49;
    opacity: 0;
    transition: opacity var(--t-base) var(--ease);
    pointer-events: none;
}
.sidebar-scrim[hidden] { display: block; }   /* keep box for transition */
body.sidebar-open .sidebar-scrim {
    opacity: 1;
    pointer-events: auto;
}

@media (max-width: 959px) {
    .app { grid-template-columns: 1fr; }

    /* Sidebar = slide-in drawer from the left. Fixed positioning so it
       overlays the workspace instead of pushing content. */
    .sidebar {
        position: fixed;
        top: 0;
        left: 0;
        bottom: 0;
        height: 100vh;
        height: 100dvh;
        width: 80vw;
        max-width: 280px;
        z-index: 50;
        transform: translateX(-100%);
        transition: transform var(--t-slow) var(--ease);
        box-shadow: var(--elev-4);
        padding-top: max(16px, env(safe-area-inset-top));
        padding-bottom: max(18px, env(safe-area-inset-bottom));
        padding-left: max(14px, env(safe-area-inset-left));
        flex-direction: column;
        overflow-y: auto;
        -webkit-overflow-scrolling: touch;
    }
    body.sidebar-open .sidebar { transform: translateX(0); }

    .nav-toggle { display: inline-flex; flex-shrink: 0; }

    .topbar {
        padding: 0 14px;
        background: var(--bg-app);
        backdrop-filter: none;
        -webkit-backdrop-filter: none;
    }
    .breadcrumb { font-size: 12px; min-width: 0; overflow: hidden; flex: 1; }
    .crumb { white-space: nowrap; overflow: hidden; text-overflow: ellipsis; }
    .topbar-actions { margin-left: auto; flex-shrink: 0; }

    /* Search trigger: icon only on phones — label + ⌘K kbd hidden. */
    .cmd-trigger { padding: 7px 10px; min-width: 40px; min-height: 40px; }
    .cmd-trigger .cmd-trigger-text,
    .cmd-trigger kbd { display: none; }

    .workspace { padding: 18px 14px 28px; max-width: 100%; }

    .card { padding: 18px 16px; border-radius: var(--r-3); }
    .card-header { gap: 10px; margin-bottom: 14px; padding-bottom: 12px; }
    .card-header h2 { font-size: 15px; }
    .card-sub { font-size: 11px; }
    .step-num { width: 26px; height: 26px; font-size: 11px; }

    .hero { grid-template-columns: 1fr; padding: 20px 18px; gap: 14px; }
    .hero h1 { font-size: 22px; line-height: 1.18; }
    .hero-lede { font-size: 13px; }
    .hero-pipeline { display: none; }

    /* Stats strip: 2-column on phone instead of 5+ slivers. */
    .stats-strip { grid-template-columns: repeat(2, 1fr); }
    .stat-tile { padding: 12px 14px; }
    .stat-val { font-size: 19px; }
    .stat-sub { font-size: 10px; }

    /* Input tabs: horizontal scroll if they don't fit. */
    .input-tabs {
        max-width: 100%;
        overflow-x: auto;
        -webkit-overflow-scrolling: touch;
        scrollbar-width: none;
    }
    .input-tabs::-webkit-scrollbar { display: none; }
    .tab { flex-shrink: 0; }

    .dropzone { padding: 28px 18px; gap: 10px; }
    .dz-icon { width: 38px; height: 38px; }
    .dz-icon svg { width: 18px; height: 18px; }
    .dz-copy strong { font-size: 13px; }
    .dz-copy span { font-size: 12px; }
    .dz-formats { font-size: 10px; gap: 3px; }

    .paste-shell { font-size: 12px; }
    .paste-gutter { min-width: 36px; padding: 9px 8px 9px 10px; font-size: 11px; }
    .paste-shell textarea { font-size: 12px; }
    .paste-actions { flex-direction: column; align-items: stretch; gap: 8px; }
    .paste-stats { text-align: center; }

    .preview { padding: 14px 16px; }
    .preview-meta { gap: 14px; }

    .setting-grid { grid-template-columns: 1fr; gap: 14px; }

    .primary-lg { padding: 14px 18px; font-size: 13px; min-height: 50px; }

    .card-header.results-header { flex-wrap: wrap; }
    .results-actions { width: 100%; justify-content: flex-end; flex-wrap: wrap; }
    .table-toolbar { flex-direction: column; align-items: stretch; gap: 8px; }
    .table-count { text-align: right; }

    .result-table-wrap { max-height: 60vh; max-height: 60dvh; }
    .result-table th, .result-table td { padding: 8px 10px; font-size: 12px; }
    .result-table td.mutations { font-size: 11px; }

    .detail-panel { padding: 16px 14px; gap: 16px; }
    .pcr-summary { gap: 14px; padding: 12px 14px; }
    .primer-grid { grid-template-columns: 1fr; }
    .primer-actions { flex-direction: column; }
    .synth-row { padding: 12px 12px; }
    .synth-row .synth-btn { max-width: 100%; }

    .mutmap-card { padding: 14px 14px 16px; }
    .mutmap-head { flex-direction: column; align-items: flex-start; gap: 8px; }
    .mutmap-canvas svg { height: 160px; }

    .run-meta { padding: 12px 14px; }
    .run-meta-pills { gap: 5px; }
    .run-methods { padding: 11px 13px; font-size: 11px; }

    /* Twist gateway modal: bottom sheet on phones. */
    .modal { padding: 0; align-items: flex-end; }
    .modal-panel {
        width: 100%;
        max-width: 100%;
        max-height: 92vh;
        max-height: 92dvh;
        border-radius: var(--r-4) var(--r-4) 0 0;
        padding-bottom: env(safe-area-inset-bottom);
        animation: panelInMobile 240ms var(--ease);
    }
    @keyframes panelInMobile {
        from { transform: translateY(12px); opacity: 0; }
        to   { transform: translateY(0); opacity: 1; }
    }
    .modal-header { padding: 16px 18px 12px; }
    .modal-body { padding: 14px 18px 22px; }
    .quote-hero-numbers { grid-template-columns: 1fr; gap: 12px; }
    .quote-hero-divider { display: none; }
    .quote-hero-val { font-size: 24px; }
    .quote-grid { grid-template-columns: 1fr 1fr; }
    .order-form-grid { grid-template-columns: 1fr; }

    .lib-row { grid-template-columns: 1fr; gap: 8px; }
    .lib-row-actions { justify-content: flex-end; }

    .hist-item { grid-template-columns: auto 1fr; }
    .hist-time { grid-column: 2 / -1; }

    .empty-art { width: 160px; }
    .empty-title { font-size: 15px; }
    .empty-sub { font-size: 12px; }

    .identify-row { flex-direction: column; align-items: stretch; gap: 8px; }
    .identify-btn { justify-content: center; }
    .identify-hit { grid-template-columns: auto 1fr; gap: 8px; }
    .identify-hit-stats { grid-column: 1 / -1; text-align: left; font-size: 10px; }

    .alphafold-viewer { height: 280px; height: 32dvh; }

    /* Toast at the bottom on phones — fits better with thumb position. */
    .toast {
        top: auto;
        bottom: 18px;
        margin-top: 0;
        margin-bottom: env(safe-area-inset-bottom);
        max-width: calc(100vw - 32px);
        transform: translate(-50%, 120%);
    }
    .toast.toast-in  { transform: translate(-50%, 0); }
    .toast.toast-out { transform: translate(-50%, 120%); }
}

/* Larger phones / small tablets — give more breathing room. */
@media (min-width: 540px) and (max-width: 959px) {
    .workspace { padding: 22px 22px 36px; }
    .card { padding: 22px 22px; }
    .hero h1 { font-size: 26px; }
    .stats-strip { grid-template-columns: repeat(3, 1fr); }
    .quote-grid { grid-template-columns: repeat(4, 1fr); }
    .order-form-grid { grid-template-columns: 1fr 1fr; }
}